SCHEMBL17045823

SCHEMBL17045823

CCOC(=O)CCSc1ncccc1-c1ncccc1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
KDM4E B2RXH2 3/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 3/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 4/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
IDO1 P14902 1/20 0.41
MEN1 O00255 1/20 0.40
BRCA1 P38398 1/20 0.40
CDC25B P30305 1/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 2/20 0.39
GLA P06280 2/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16390504 0.78 ALDH1A1 (0.42) LMNAKDM4EPOLBMAPTKMT2A
SCHEMBL29340344 0.76 ALDH1A1 (0.51) LMNAKDM4EPOLBMAPTKMT2A
SCHEMBL16333977 0.74 FFAR4 (0.53) MAPT
SCHEMBL17695384 0.73 ALDH1A1 (0.38) LMNAKDM4EPOLBMAPTKMT2A
SCHEMBL16334241 0.73 FFAR4 (0.50) MAPT
SCHEMBL16335097 0.73 FFAR4 (0.49) MAPT
SCHEMBL25871104 0.73 KDM4E (0.45) KDM4EPOLBMAPTKMT2AHPGD
SCHEMBL433166 0.71 LMNA (0.74) LMNAKDM4EPOLBMAPTKMT2A
SCHEMBL24406739 0.71 LMNA (0.43) LMNAKDM4EMAPTKMT2AHPGD
SCHEMBL10132049 0.71 MAPT (0.52) LMNAKDM4EMAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9590195-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-03-07 US disclosed
US-9590195-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-03-07 US disclosed
US-9590195-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-03-07 US disclosed
US-20150249223-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-20150249223-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-20150249223-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150249223-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA1, IGF2R, LIFR LMNA 1729/4885KDM4E 2371/4885POLB 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.