Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17046033 | 0.81 | TSHR (0.45) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL10711212 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL17053597 | 0.77 | TSHR (0.42) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL16405963 | 0.77 | TSHR (0.42) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL14802907 | 0.77 | TSHR (0.42) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL17053547 | 0.77 | TSHR (0.42) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL16582974 | 0.75 | TSHR (0.37) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL16582971 | 0.74 | TSHR (0.39) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL17046235 | 0.74 | TSHR (0.39) | TSHRALDH1A1GLAADRA2AKCNH2 | |
| SCHEMBL2269712 | 0.73 | TP53 (0.38) | TSHRALDH1A1GLAADRA2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294250-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2019-05-21 | — | — | US | disclosed |
| EP-3395822-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | Versum Materials US, LLC (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9758534-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2017-09-12 | — | — | US | disclosed |
| US-20170204120-A1 | Organoaminosilanes and Methods for Making Same | VERSUM MATERIALS US, LLC (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170204120-A1 | Organoaminosilanes and Methods for Making Same | VERSUM MATERIALS US, LLC (US) | 2017-07-20 | — | — | US | disclosed |
| US-20160168169-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160168169-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-06-16 | — | — | US | disclosed |
| US-9233990-B2 | Organoaminosilanes and methods for making same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233990-B2 | Organoaminosilanes and methods for making same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20150246937-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150246937-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150246937-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| EP-2913334-A1 | Organoaminosilanes and methods for making same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246937-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
| US-20170204120-A1 | Organoaminosilanes and Methods for Making Same | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
| US-10294250-B2 | Organoaminosilanes and methods for making same | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
| US-20160168169-A1 | ORGANOAMINOSILANES AND METHODS FOR MAKING SAME | DDAH1, IDUA, DDT | TSHR 3989/4885ALDH1A1 418/4885GLA 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.