SCHEMBL17045988

SCHEMBL17045988

CCC(C)N([SiH2]C(C)[SiH2]N(C(C)CC)C1CCCCC1)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.35
ADH1A P07327 3/20 0.34
ADH1C P00326 2/20 0.34
ADH1B P00325 1/20 0.34
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17046221 0.98 SHBG (0.32) SHBGADH1AADH1CADH1B
SCHEMBL17053490 0.86 SHBG (0.37) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17053614 0.85 SHBG (0.33) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17046217 0.84 SHBG (0.35) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17053491 0.83 SHBG (0.33) SHBGADH1AADH1CADH1B
SCHEMBL17053585 0.82 SHBG (0.34) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17053472 0.82 SHBG (0.34) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17053615 0.82 SHBG (0.30) SHBG
SCHEMBL17053536 0.82 SHBG (0.34) SHBGADH1AADH1CADH1BMEN1
SCHEMBL17046202 0.82 SHBG (0.32) SHBGADH1AADH1CADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294250-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2019-05-21 US disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
EP-2913334-A1 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT SHBG 694/4885ADH1A 160/4885ADH1C 498/4885
US-20170204120-A1 Organoaminosilanes and Methods for Making Same DDAH1, IDUA, DDT SHBG 694/4885ADH1A 160/4885ADH1C 498/4885
US-10294250-B2 Organoaminosilanes and methods for making same DDAH1, IDUA, DDT SHBG 694/4885ADH1A 160/4885ADH1C 498/4885
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT SHBG 694/4885ADH1A 160/4885ADH1C 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.