SCHEMBL1704609

SCHEMBL1704609

[CH2]C(C)C1CC=C(C)CC1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
PTPN1 P18031 1/20 0.37
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CNR2 P34972 1/20 0.32
PPARA Q07869 1/20 0.32
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
CHRNA7 P36544 1/20 0.31
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933973 0.83 LMNA (0.44) LMNAPTPN1MEN1KMT2ACNR2
SCHEMBL3851126 0.83 LMNA (0.44) LMNAPTPN1MEN1KMT2ACNR2
SCHEMBL16796012 0.83 LMNA (0.44) LMNAPTPN1MEN1KMT2ACNR2
SCHEMBL736990 0.83 LMNA (0.44) LMNAPTPN1MEN1KMT2ACNR2
SCHEMBL6882235 0.83 LMNA (0.44) LMNAPTPN1MEN1KMT2ACNR2
SCHEMBL14764978 0.79 LMNA (0.41) LMNAPTPN1MEN1KMT2ACYP3A4
SCHEMBL6402023 0.79 LMNA (0.46) LMNAPTPN1MEN1KMT2ACYP3A4
SCHEMBL4231093 0.79 LMNA (0.42) LMNAPTPN1MEN1KMT2ACYP3A4
SCHEMBL21913451 0.77 LMNA (0.47) LMNAPTPN1MEN1KMT2ACYP3A4
SCHEMBL24133233 0.76 LMNA (0.39) LMNAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6033597-A COMPOUNDING AGENT COMPRISING A MIXTURE OF A POLYSILOXANE HAVING AN ALKOXYSILYL GROUP; AND A SULFUR CONTAINING SILANE COUPLER. THE YOKOHAMA RUBBER CO., LTD. (JP) 2000-03-07 US claimed
US-4138542-A MOLDING MATERIALS, COATINGS, ADHESIVES, TEXTILE AND PAPER FINISHES BASF AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
US-20200102272-A1 SYNTHESIS OF SUBSTITUTED ENONES HENKEL AG & CO. KGAA (DE) 2020-04-02 US disclosed
EP-3628658-A1 SYNTHESIS OF SUBSTITUTED ENONES Henkel AG & Co. KGaA (DE) 2020-04-01 EP disclosed
EP-2145042-B1 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2018-01-17 EP disclosed
EP-2760904-A1 METHOD FOR PRODUCING A MOLDED FOAM ELEMENT Eurofoam GmbH (AT) 2014-08-06 EP disclosed
EP-1981936-B1 FLUID RESERVOIR HENKEL AG & CO KGAA (DE) 2013-04-10 EP disclosed
WO-2013034416-A1 ANTIMICROBIAL METHOD AND COMPOSITION UNILEVER N.V. (NL) 2013-03-14 WO disclosed
WO-2013034581-A1 ANTIMICROBIAL COMPOSITION COMPRISING THYMOL AND A TERPINYL DERIVATIVE UNILEVER N.V. (NL) 2013-03-14 WO disclosed
EP-2069468-B1 PERFUME DISPENSING SYSTEM HENKEL AG & CO KGAA (DE) 2012-12-26 EP disclosed
US-6337361-B1 RUBBER WITH SILICA, SILANE COUPLER AND INERT POWDER THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-01-08 US disclosed
US-6177505-B1 IMPROVES THE PROCESSABILITY OF THE UNVULCANIZED RUBBER COMPOSITION, WITHOUT SUBSTANTIALLY IMPAIRING THE PROPERTIES OF THE SILICA-CONTAINING VULCANIZING RUBBER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2001-01-23 US disclosed
US-6121347-A A REINFORCING FILLER COMPRISING INERT POWDER COUPLED WITH A SILANE COUPLING AGENT TO A POLYSILOXANE RESIN OR A SILOXANE COMPOUND; IMPROVING LOW HEAT GENERATION, THE MODULUS AND THE ABRASION RESISTANCE OF THE RUBBER THE YOKOHAMA RUBBER CO., LTD. (JP) 2000-09-19 US disclosed
US-6033597-A COMPOUNDING AGENT COMPRISING A MIXTURE OF A POLYSILOXANE HAVING AN ALKOXYSILYL GROUP; AND A SULFUR CONTAINING SILANE COUPLER. THE YOKOHAMA RUBBER CO., LTD. (JP) 2000-03-07 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed
EP-0761748-A2 Polysiloxane-containing rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 1997-03-12 EP disclosed
US-4138542-A MOLDING MATERIALS, COATINGS, ADHESIVES, TEXTILE AND PAPER FINISHES BASF AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed
US-4138542-A MOLDING MATERIALS, COATINGS, ADHESIVES, TEXTILE AND PAPER FINISHES BASF AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200102272-A1 SYNTHESIS OF SUBSTITUTED ENONES ENO1, CYP51A1, MAP7 LMNA 1149/4885PTPN1 3597/4885MEN1 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.