⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL3783124 | 0.47 | — | — | |
| Urea SCHEMBL28191757 | 0.44 | — | — | |
| Urea SCHEMBL8855160 | 0.44 | — | — | |
| Carbamic Acid SCHEMBL674697 | 0.44 | — | — | |
| Urea SCHEMBL11630935 | 0.44 | — | — | |
| Urea SCHEMBL4797526 | 0.44 | — | — | |
| SCHEMBL22027687 | 0.43 | — | — | |
| Urea SCHEMBL7756359 | 0.43 | LMNA (1.00) | — | |
| Urea SCHEMBL8560069 | 0.43 | LMNA (1.00) | — | |
| Urea SCHEMBL20641124 | 0.43 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627634-B1 | A NEW DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | DEUTSCHES KREBSFORSCH (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-20130274440-A1 | DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2013-10-17 | — | — | US | disclosed |
| EP-2627634-A1 | A NEW DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | Deutsches Krebsforschungszentrum (DE) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012048877-A1 | A NEW DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2012-04-19 | — | — | WO | disclosed |
| EP-2441754-A1 | A new dimedon derivative and a method for the purification of PNA and peptide oligomers | Deutsches Krebsforschungszentrum (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2044035-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007144200-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-21 | — | — | WO | disclosed |
| EP-1867638-A1 | Procedure for the Conection of two Molecules via Diels-Alder Reactions with Inverse Electron Demand | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-19 | — | — | EP | disclosed |