Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28478547 | 0.94 | LMNA (0.86) | — | |
| Urea SCHEMBL3783124 | 0.94 | — | — | |
| Urea SCHEMBL7040620 | 0.88 | — | — | |
| Urea SCHEMBL6361905 | 0.88 | — | — | |
| Urea SCHEMBL11630935 | 0.88 | — | — | |
| Urea SCHEMBL23779965 | 0.88 | — | — | |
| Urea SCHEMBL11590334 | 0.88 | — | — | |
| Urea SCHEMBL11594201 | 0.88 | — | — | |
| Urea SCHEMBL10948406 | 0.88 | — | — | |
| Urea SCHEMBL2240218 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106182298-A | Preparation method of nano calcium carbonate in-situ modified bamboo wood | 国际竹藤中心 | 2016-12-07 | — | — | CN | claimed |
| EP-0457891-A4 | ANIMAL FEED BLOCK COMPOSITION | — | 1992-03-11 | — | — | EP | claimed |
| EP-0457891-A1 | ANIMAL FEED BLOCK COMPOSITION | CARGILL, INCORPORATED (US) | 1991-11-27 | — | — | EP | claimed |
| US-5068114-A | Weather resistant, stackable food blocks | CARGILL, INCORPORATED (US) | 1991-11-26 | — | — | US | claimed |
| WO-1991007882-A1 | ANIMAL FEED BLOCK COMPOSITION | CARGILL, INCORPORATED (US) | 1991-06-13 | — | — | WO | claimed |
| CN-117211122-A | Method for improving slag bottom ash roadbed through EICP solidification | 苏州大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-116219529-A | Method for preparing dendritic calcium sulfate by disposing waste liquid from gasified ash | 青岛惠城环保科技集团股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114592498-A | Method for inducing calcium carbonate precipitation by combining plant urease with urease inhibitor | 西安建筑科技大学 | 2022-06-07 | — | — | CN | disclosed |
| WO-2020093704-A1 | MICROBIAL MODIFICATION FILLING MATERIAL AND PREPARATION METHOD | 中国矿业大学 | 2020-05-14 | — | — | WO | disclosed |
| CN-110698104-A | Method for repairing cement-based material cracks by using soybean urease | 太原理工大学 | 2020-01-17 | — | — | CN | disclosed |
| US-10399130-B2 | Methods and systems for in situ temporary containment of shallow contaminated soils | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-09-03 | — | — | US | disclosed |
| US-10328179-B2 | Bone matrix compositions and methods | WARSAW ORTHOPEDIC, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| WO-1989009787-A2 | OSTEOGENIC DEVICES | CREATIVE BIOMOLECULES, INC. (US) | 1989-10-19 | — | — | WO | disclosed |
| US-4528204-A | Preparation of hydrolyzed collagen-containing products from non-gelled liquid hydrolyzed collagen concentrate and gelled products prepared therefrom | DYNAGEL, INCORPORATED (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0073908-B1 | METHOD OF PREPARING A PRODUCT CONTAINING GELLED, HYDROLYZED COLLAGEN | DYNAGEL, Incorporated (US) | 1985-03-13 | — | — | EP | disclosed |
| US-4455256-A | Bone morphogenetic protein | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-06-19 | — | — | US | disclosed |
| US-4426443-A | Preparation of hydrolyzed collagen-containing products from non-gelled, liquid hydrolyzed collagen concentrate and gelled products prepared therefrom | DYNAGEL, INCORPORATED (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0073908-A1 | Method of preparing a product containing gelled, hydrolyzed collagen | DYNAGEL, Incorporated (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4366096-A | CONSTRUCTION MATERIALS | ABRAMS, BERNICE | 1982-12-28 | — | — | US | disclosed |
| US-4294753-A | Bone morphogenetic protein process | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1981-10-13 | — | — | US | disclosed |