Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047747 | 0.81 | MEN1 (0.40) | MEN1KMT2AMGLLHSD11B1NOTUM | |
| SCHEMBL17047790 | 0.76 | RXFP1 (0.38) | MEN1KMT2AATMALDH1A1KDM4E | |
| SCHEMBL17047801 | 0.73 | RXFP1 (0.43) | MEN1KMT2AMGLLHSD11B1NOTUM | |
| SCHEMBL29564792 | 0.65 | MGLL (0.56) | MEN1KMT2AMGLLNOTUMEPHX2 | |
| SCHEMBL19439527 | 0.65 | MGLL (0.56) | MEN1KMT2AMGLLNOTUMEPHX2 | |
| SCHEMBL17047759 | 0.64 | XPO1 (0.40) | MEN1KMT2AHTTNPSR1POLB | |
| SCHEMBL20320588 | 0.63 | — | — | |
| SCHEMBL17047716 | 0.62 | MEN1 (0.46) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL19605722 | 0.62 | GRM2 (0.43) | MEN1KMT2AMGLLHSD11B1ALDH1A1 | |
| SCHEMBL17537372 | 0.62 | MEN1 (0.58) | MEN1KMT2AMGLLNOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110808-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| US-9751867-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| EP-3110808-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-22 | — | — | US | disclosed |
| WO-2015128321-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368900-A1 | PLANT GROWTH REGULATING COMPOUNDS | GHDC, GAK, EIF4G2 | MEN1 4325/4885KMT2A 3798/4885MGLL 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.