SCHEMBL17047871

SCHEMBL17047871

COc1ccc(-c2nc(COCCCc3ccccn3)co2)cc1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
LMNA P02545 2/20 0.42
TSHR P16473 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 5/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SYK P43405 5/20 0.41
ACHE P22303 1/20 0.41
ALOX15 P16050 1/20 0.40
MAPK1 P28482 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ABCB1 P08183 1/20 0.39
ABCC1 P33527 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 2/20 0.39
PDE4A P27815 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047853 0.92 SYK (0.40) SYKACHEABCB1ABCC1NPC1
SCHEMBL17047862 0.90 ALDH1A1 (0.47) MAPTLMNATSHRALDH1A1MEN1
SCHEMBL17047898 0.86 ACP1 (0.45) MAPTL3MBTL1ALDH1A1SYKNPC1
SCHEMBL17047888 0.85 KDM4E (0.37) MAPTLMNATSHRL3MBTL1ALDH1A1
SCHEMBL17047946 0.82 FFAR1 (0.42) MAPTLMNATSHRALDH1A1MEN1
SCHEMBL17047866 0.82 SYK (0.49) MAPTLMNAL3MBTL1ALDH1A1MEN1
SCHEMBL17047881 0.82 SYK (0.45) MAPTALDH1A1MEN1KMT2ASYK
SCHEMBL17047889 0.81 TAS1R3 (0.40) ALDH1A1HSD17B10KDM4EHPGDNPC1
SCHEMBL17047954 0.81 FFAR1 (0.43) TSHRKDM4EPOLB
SCHEMBL17047890 0.80 ACP1 (0.47) L3MBTL1SYKNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015129755-A1 NOVEL COMPOUND AND TEXTURE IMPROVER CONTAINING SAID COMPOUND 味の素株式会社 2015-09-03 WO disclosed