SCHEMBL17047950

SCHEMBL17047950

CC(C)(C)c1ccc(-c2nc(COCc3ccccn3)co2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
NPSR1 Q6W5P4 2/20 0.40
TP53 P04637 2/20 0.39
POLB P06746 1/20 0.39
FFAR1 O14842 1/20 0.38
SYK P43405 5/20 0.37
PPARG P37231 4/20 0.37
PPARA Q07869 4/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ADRB2 P07550 1/20 0.37
AURKB Q96GD4 3/20 0.36
INCENP Q9NQS7 3/20 0.36
HDAC4 P56524 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047857 0.84 FFAR1 (0.44) ALDH1A1NPC1RAB9ANPSR1TP53
SCHEMBL17047850 0.84 SYK (0.53) NPC1RAB9AFFAR1SYKPPARG
SCHEMBL17047855 0.83 PPARA (0.41) ALDH1A1NPC1RAB9AFFAR1SYK
SCHEMBL17047944 0.82 FFAR1 (0.47) ALDH1A1NPC1RAB9AFFAR1SYK
SCHEMBL17047896 0.81 LTA4H (0.48) ALDH1A1FFAR1SYKPPARGPPARA
SCHEMBL17047951 0.81 PPARG (0.49) TP53FFAR1SYKPPARGPPARA
SCHEMBL17047885 0.81 MAPT (0.41) ALDH1A1NPC1RAB9ATP53FFAR1
SCHEMBL17047862 0.80 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ANPSR1POLB
SCHEMBL17047935 0.79 ERBB2 (0.47) ALDH1A1NPC1RAB9A
SCHEMBL17047934 0.79 ERBB2 (0.47) ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015129755-A1 NOVEL COMPOUND AND TEXTURE IMPROVER CONTAINING SAID COMPOUND 味の素株式会社 2015-09-03 WO disclosed
WO-2015129755-A1 NOVEL COMPOUND AND TEXTURE IMPROVER CONTAINING SAID COMPOUND 味の素株式会社 2015-09-03 WO disclosed