Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271332 | 0.98 | HTR6 (0.48) | HTR6HTR2CPOLB | |
| Hydrochloric Acid SCHEMBL28208905 | 0.88 | HTR6 (0.36) | HTR6HTR2C | |
| SCHEMBL8146446 | 0.76 | HTR6 (0.47) | HTR6HTR2CRAD52 | |
| SCHEMBL10465527 | 0.76 | HTR6 (0.47) | HTR6HTR2CPOLBRAD52 | |
| SCHEMBL24977006 | 0.75 | HTR6 (0.41) | HTR6HTR2C | |
| SCHEMBL10325516 | 0.74 | HTR6 (0.46) | HTR6HTR2C | |
| SCHEMBL22303905 | 0.73 | HTR6 (0.48) | HTR6HTR2CPOLB | |
| SCHEMBL29118976 | 0.73 | HTR6 (0.48) | HTR6HTR2C | |
| SCHEMBL8594895 | 0.73 | PHGDH (0.33) | POLB | |
| SCHEMBL27815135 | 0.73 | HTR6 (0.44) | HTR6HTR2CCHRM5CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110803-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Mutabilis (FR) | 2017-01-04 | — | — | EP | claimed |
| WO-2015128333-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LABORATOIRE BIODIM (FR) | 2015-09-03 | — | — | WO | claimed |
| EP-3110803-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Mutabilis (FR) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015128333-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LABORATOIRE BIODIM (FR) | 2015-09-03 | — | — | WO | disclosed |