SCHEMBL8146446

SCHEMBL8146446

NC1CNCCN1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.47
HTR2C P28335 1/20 0.35
RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29118976 0.98 HTR6 (0.48) HTR6HTR2C
SCHEMBL8518847 0.80 HTR6 (0.47) HTR6HTR2C
SCHEMBL17048236 0.76 HTR6 (0.47) HTR6HTR2CRAD52
SCHEMBL10465527 0.76 HTR6 (0.47) HTR6HTR2CRAD52
SCHEMBL6663565 0.76 HTR6 (0.43) HTR6HTR2C
SCHEMBL10325516 0.74 HTR6 (0.46) HTR6HTR2C
SCHEMBL28271332 0.73 HTR6 (0.48) HTR6HTR2C
SCHEMBL22303905 0.73 HTR6 (0.48) HTR6HTR2C
SCHEMBL27815135 0.73 HTR6 (0.44) HTR6HTR2CRAD52
SCHEMBL15556247 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1269719-A Aroylpiperazines for modulating sexual activity NORTRAN PHARMACEUTICALS INC (CA) 2000-10-11 CN disclosed
EP-1001776-A1 AROYLPIPERAZINES FOR MODULATING SEXUAL ACTIVITY Nortran Pharmaceuticals Inc. (CA) 2000-05-24 EP disclosed
WO-1999002159-A1 AROYLPIPERAZINES FOR MODULATING SEXUAL ACTIVITY NORTRAN PHARMACEUTICALS INC. (CA) 1999-01-21 WO disclosed