SCHEMBL17048264

SCHEMBL17048264

CC(C)(C)[Si](C)(C)OC[C@H](O)CO

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.34
AR P10275 5/20 0.33
LMNA P02545 3/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 2/20 0.32
KDM4E B2RXH2 2/20 0.32
AGTR1 P30556 1/20 0.32
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428149 1.00 USP2 (0.34) USP2ARLMNAALDH1A1CYP1A2
SCHEMBL17048382 1.00 USP2 (0.34) USP2ARLMNAALDH1A1CYP1A2
SCHEMBL4420207 0.89 MAPK1 (0.32) MAPK1
SCHEMBL10447623 0.83 THRB (0.36)
SCHEMBL3608074 0.83 TSHR (0.32) TSHR
SCHEMBL5241702 0.83 KDM4E (0.34) KDM4E
SCHEMBL1628831 0.83 TSHR (0.32) TSHR
SCHEMBL2962445 0.83 TSHR (0.32) TSHR
SCHEMBL59285 0.81 AR (0.36) AR
SCHEMBL59286 0.81 AR (0.36) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736236-B Preparation method of hydroxyl-protected intermediate, phosphatidylethanolamine compound and preparation method thereof 凯莱英生命科学技术(天津)有限公司 2024-08-23 CN disclosed
CN-117736236-A Preparation method of hydroxyl-protected intermediate, phosphatidylethanolamine compound and preparation method thereof 凯莱英生命科学技术(天津)有限公司 2024-03-22 CN disclosed
EP-3110789-B1 DERIVATIVES OF POLYHYDROXY COMPOUNDS RATIOPHARM GMBH (DE) 2019-05-22 EP disclosed
US-9796659-B2 Derivatives of polyhydroxy compounds RATIOPHARM GMBH (DE) 2017-10-24 US disclosed
US-9796659-B2 Derivatives of polyhydroxy compounds RATIOPHARM GMBH (DE) 2017-10-24 US disclosed
US-9796659-B2 Derivatives of polyhydroxy compounds RATIOPHARM GMBH (DE) 2017-10-24 US disclosed
US-20170001945-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS RATIOPHARM GMBH (DE) 2017-01-05 US disclosed
US-20170001945-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS RATIOPHARM GMBH (DE) 2017-01-05 US disclosed
US-20170001945-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS RATIOPHARM GMBH (DE) 2017-01-05 US disclosed
EP-3110789-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS ratiopharm GmbH (DE) 2017-01-04 EP disclosed
WO-2015128488-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS RATIOPHARM GMBH (DE) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170001945-A1 DERIVATIVES OF POLYHYDROXY COMPOUNDS TPMT, FH, FAH USP2 1561/4885AR 3999/4885LMNA 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.