SCHEMBL1704847

SCHEMBL1704847

N#CCCN1CCNCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ALDH1A1 P00352 3/20 0.68
PKM P14618 1/20 0.68
MAPT P10636 2/20 0.45
CXCR4 P61073 2/20 0.43
HRH2 P25021 2/20 0.40
HRH1 P35367 2/20 0.40
HRH3 Q9Y5N1 2/20 0.40
HSD17B10 Q99714 2/20 0.39
GAA P10253 3/20 0.39
TSHR P16473 1/20 0.39
SIGMAR1 Q99720 1/20 0.37
RAD52 P43351 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905479 1.00 POLB (1.00) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL7510066 0.98 POLB (0.95) POLBSMN1; SMN2ALDH1A1PKMMAPT
Hydrochloric Acid SCHEMBL2010734 0.98 POLB (0.95) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL18975385 0.92 POLB (0.84) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL7506605 0.88 POLB (0.78) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL1546711 0.86 POLB (0.76) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL16265654 0.86
Piperazine SCHEMBL27980951 0.85 POLB (0.73) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL1344289 0.82 ALDH1A1 (1.00) POLBSMN1; SMN2ALDH1A1PKMMAPT
SCHEMBL383162 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
EP-2010496-B1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS ASTRAZENECA AB (SE) 2010-08-25 EP claimed
US-20090054411-A1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS ASTRAZENECA AB (SE) 2009-02-26 US claimed
EP-2010496-A1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS AstraZeneca AB (SE) 2009-01-07 EP claimed
WO-2007119046-A1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS ASTRAZENECA AB (SE) 2007-10-25 WO claimed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US claimed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US claimed
US-4609698-A LIGHT STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1986-09-02 US claimed
US-RE29834-E PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US claimed
US-20260146042-A1 PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2026-05-28 US disclosed
CN-116829545-B Substituted pyrazolylpiperidine carboxylic acids 拜耳公司 2026-05-15 CN disclosed
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors INCYTE CORPORATION (US) 2026-01-27 US disclosed
US-12491272-B2 Stable, concentrated radionuclide complex solutions ADVANCED ACCELERATOR APPLICATIONS SA (FR) 2025-12-09 US disclosed
US-4105664-A Dibenz[b,f]oxepin derivatives HOFFMANN-LA ROCHE INC. (US) 1978-08-08 US disclosed
US-4100173-A DEPRESSANTS, SCHIZOPHRENIA, TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1978-07-11 US disclosed
US-4091023-A ANTISCHIZOPHRENIA AGENTS, TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1978-05-23 US disclosed
US-4032525-A CNS DEPRESSANTS, NEUROLEPTICS HOFFMANN-LA ROCHE INC. (US) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534463-B2 Substituted tricyclic compounds as FGFR inhibitors FGFR3, FGFR1, FGFR4 POLB 1617/4885SMN1; SMN2 128/4885ALDH1A1 2330/4885
US-20260146042-A1 PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES CDK9, CDK6, CDK7 POLB 837/4885SMN1; SMN2 3529/4885ALDH1A1 3935/4885
US-12491272-B2 Stable, concentrated radionuclide complex solutions EPOR, PAICS, XPO5 POLB 184/4885SMN1; SMN2 1096/4885ALDH1A1 3532/4885
US-20090054411-A1 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS CSF1R, CSF3R, FLT3 POLB 3210/4885SMN1; SMN2 4289/4885ALDH1A1 1650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.