Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 6/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17098475 | 0.93 | EGFR (0.34) | LPAR1LPAR5ALDH1A1KDM4ELMNA | |
| SCHEMBL17098472 | 0.93 | EGFR (0.34) | LPAR1LPAR5ALDH1A1KDM4ELMNA | |
| SCHEMBL17048962 | 0.91 | ALDH1A1 (0.34) | LPAR1LPAR5ALDH1A1TAS2R14BACE1 | |
| SCHEMBL17048992 | 0.84 | LPAR1 (0.35) | LPAR1LPAR5ALDH1A1TAS2R14KDM4E | |
| SCHEMBL17097660 | 0.84 | LPAR1 (0.35) | LPAR1LPAR5ALDH1A1TAS2R14KDM4E | |
| SCHEMBL17099285 | 0.84 | EGFR (0.35) | LPAR1LPAR5ALDH1A1KDM4ELMNA | |
| SCHEMBL17099286 | 0.84 | EGFR (0.35) | LPAR1LPAR5ALDH1A1KDM4ELMNA | |
| SCHEMBL17048900 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TAS2R14MAPT | |
| SCHEMBL17110300 | 0.83 | LPAR1 (0.31) | LPAR1LPAR5ALDH1A1MAPT | |
| SCHEMBL17098573 | 0.82 | BACE1 (0.35) | ALDH1A1TAS2R14BACE1BACE2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |