Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099285 | 0.92 | EGFR (0.35) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL17099286 | 0.92 | EGFR (0.35) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL17048871 | 0.91 | LPAR1 (0.33) | ALDH1A1TAS2R14KDM4ELMNAMAPT | |
| SCHEMBL17098281 | 0.88 | POLB (0.34) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL17098282 | 0.88 | POLB (0.34) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL17117925 | 0.88 | ALDH1A1 (0.35) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL17097660 | 0.87 | LPAR1 (0.35) | ALDH1A1TAS2R14KDM4ELMNAMAPT | |
| SCHEMBL17048992 | 0.87 | LPAR1 (0.35) | ALDH1A1TAS2R14KDM4ELMNAMAPT | |
| SCHEMBL17098181 | 0.86 | — | — | |
| SCHEMBL17098182 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |