Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049139 | 0.89 | PDK2 (0.35) | PDK2 | |
| SCHEMBL17049123 | 0.89 | PDK2 (0.30) | PDK2 | |
| SCHEMBL869547 | 0.85 | PDK2 (0.42) | PDK2SLC6A3CA1CA2CNR1 | |
| SCHEMBL17049167 | 0.85 | PTGES (0.34) | — | |
| SCHEMBL1354020 | 0.83 | PDK2 (0.38) | PDK2ABL1 | |
| SCHEMBL23778641 | 0.82 | KDM4E (0.39) | PDK2SLC6A3BDKRB1ABL1CA1 | |
| SCHEMBL362563 | 0.82 | KDM4E (0.39) | PDK2SLC6A3BDKRB1ABL1CA1 | |
| SCHEMBL3667455 | 0.82 | PDK2 (0.36) | PDK2HPGD | |
| SCHEMBL1354206 | 0.82 | PDK2 (0.36) | PDK2 | |
| SCHEMBL3667734 | 0.82 | PDK2 (0.36) | PDK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459019-B | Oxazoline compounds | 巴斯夫欧洲公司 | 2020-01-17 | — | — | CN | disclosed |
| US-10226045-B2 | Azoline compounds | BASF SE (DE) | 2019-03-12 | — | — | US | disclosed |
| EP-3110811-B1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2018-11-07 | — | — | EP | disclosed |
| US-20180235226-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2018-08-23 | — | — | US | disclosed |
| US-9968087-B2 | Azoline compounds | BASF SE (DE) | 2018-05-15 | — | — | US | disclosed |
| EP-3110811-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-20160366887-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2016-12-22 | — | — | US | disclosed |
| WO-2015128358-A1 | AZOLINE COMPOUNDS | BASF SE (DE) | 2015-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226045-B2 | Azoline compounds | CCNB2, CCNB1, CYP1B1 | PDK2 1507/4885SLC6A3 4309/4885BDKRB1 396/4885 |
| US-20160366887-A1 | AZOLINE COMPOUNDS | CCNB2, CCNB1, CYP1B1 | PDK2 1507/4885SLC6A3 4309/4885BDKRB1 396/4885 |
| US-20180235226-A1 | AZOLINE COMPOUNDS | CCNB2, CCNB1, CYP1B1 | PDK2 1507/4885SLC6A3 4309/4885BDKRB1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.