Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 14/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118680 | 0.77 | CTSL (0.77) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL14007657 | 0.77 | CTSL (0.69) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL4126228 | 0.76 | CTSL (0.72) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL11332452 | 0.76 | CTSL (0.72) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL150166 | 0.76 | CTSL (0.72) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL7331328 | 0.76 | CTSL (0.71) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL8119601 | 0.75 | HDAC6 (0.64) | — | |
| SCHEMBL15665360 | 0.75 | CTSL (0.70) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL15665359 | 0.75 | CTSL (0.70) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL4438043 | 0.75 | CTSL (0.70) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120779-B2 | Inhibitors of HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-09-01 | — | — | US | disclosed |