Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.72 |
| ▸ | CTSS | P25774 | 2/20 | 0.72 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.69 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.69 |
| ▸ | MME | P08473 | 1/20 | 0.64 |
| ▸ | ECE1 | P42892 | 1/20 | 0.64 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150166 | 1.00 | CTSL (0.72) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL4126228 | 1.00 | CTSL (0.72) | CTSLCTSSSIRT2SIRT1MME | |
| Hydrochloric Acid SCHEMBL4438043 | 0.99 | CTSL (0.70) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL17279329 | 0.96 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL11308449 | 0.96 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL17694104 | 0.96 | SIRT2 (0.74) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL2963543 | 0.95 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL21357647 | 0.95 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL7689520 | 0.95 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1MME | |
| SCHEMBL4787188 | 0.95 | SIRT2 (0.76) | CTSLCTSSSIRT2SIRT1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-20170114080-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2017-04-27 | — | — | US | disclosed |
| US-4288432-A | ANALGESICS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114080-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | GATD3, GABRR2, GABRR3 | CTSL 4880/4885CTSS 4782/4885SIRT2 388/4885 |
| US-11679090-B2 | Modulators of Sestrin-GATOR2 interaction and uses thereof | GATD3, GABRR2, GABRR3 | CTSL 4880/4885CTSS 4782/4885SIRT2 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.