Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15868340 | 0.86 | CA12 (0.38) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL15868313 | 0.82 | BRD4 (0.35) | CA12CA9NPC1RAB9AACSS2 | |
| SCHEMBL17949365 | 0.82 | CNR2 (0.34) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL29549778 | 0.80 | CA12 (0.36) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL17941388 | 0.80 | CA12 (0.36) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL15426342 | 0.80 | NLRP3 (0.45) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL15275086 | 0.77 | NPC1 (0.45) | CA12CA9CA1CA2NPC1 | |
| SCHEMBL28511144 | 0.75 | DDR1 (0.35) | ACSS2CNR2RORC | |
| SCHEMBL15863356 | 0.74 | POLB (0.43) | ACSS2RORC | |
| SCHEMBL10249057 | 0.72 | SMN1; SMN2 (0.42) | CA12CA9CA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120823-B2 | Fused heterocyclic compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |