Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8163839 | 0.98 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Fluoride SCHEMBL7640655 | 0.98 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL271905 | 0.98 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL8754923 | 0.98 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Bromide SCHEMBL6908313 | 0.98 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL7766826 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Methyl Alcohol SCHEMBL7766797 | 0.96 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Dimethylamine SCHEMBL8357752 | 0.94 | KDM4E (0.37) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| Toluene SCHEMBL7807743 | 0.91 | LMNA (0.37) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL6555216 | 0.87 | TSHR (0.42) | HTR2ASIGMAR1KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834514-B1 | Process for synthesizing metallocene compounds | KANTO KAGAKU (JP) | 2003-10-22 | — | — | EP | claimed |
| EP-1058694-B1 | Catalyst system, method for its production and its use for the polymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-0574597-B2 | Process for the preparation of bridged, chiral metallocene catalysts of the bisindenyl type | BASELL POLYOLEFINE GMBH (DE) | 2002-06-26 | — | — | EP | claimed |
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | claimed |
| EP-0574597-B1 | Process for the preparation of bridged, chiral metallocene catalysts of the bisindenyl type | HOECHST AG (DE) | 1998-01-21 | — | — | EP | claimed |
| US-11643533-B2 | Film, method of producing film, and bag | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11472899-B2 | Ethylene-α-olefin copolymer, method of producing ethylene-α-olefin copolymer, ethylene-based resin composition, and film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-10-18 | — | — | US | disclosed |
| EP-2173778-B1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2173778-A1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | Basell Polyolefine GmbH (DE) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009015804-A1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2009-02-05 | — | — | WO | disclosed |
| US-6753378-B2 | GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS | MITSUI CHEMICALS, INC. (JP) | 2004-06-22 | — | — | US | disclosed |
| EP-1114832-B1 | Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2003-10-22 | — | — | EP | disclosed |
| EP-0729983-A2 | Process for the production of cycloolefin random copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0719803-A2 | Process for the production of cycloolefin random copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0719595-A1 | Process for manufacturing a polyolefin coating, substrate coated with that coating, and its use for contact with moving powders | ELF ATOCHEM S.A. (FR) | 1996-07-03 | — | — | EP | disclosed |
| EP-0710663-A1 | Boron-containing compound, its polymer, catalyst comprising the polymer and metallocene compound, and process for producing polyolefin | Japan Polyolefins Co., Ltd. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5476903-A | Composition containing copolymer of alpha-olefin and polyene with another polyolefin polymerized in presence of prepolymerized catalyst containing said copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| EP-0678530-A1 | Process for production of cyclic olefin copolymers and copolymers produced by said process | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-25 | — | — | EP | disclosed |
| EP-0634421-A1 | Process for gas phase polymerization of olefin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5371146-A | A blends of ethylene-(alpha)olefins copolymers has high transparency, high strength, blocking resistance, good melt flowability and tension | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |