Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GRM8 | O00222 | 2/20 | 0.31 |
| ▸ | GRM6 | O15303 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040298 | 1.00 | APLNR (0.38) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL17049843 | 1.00 | APLNR (0.38) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL20657000 | 0.83 | APLNR (0.41) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL11321445 | 0.83 | GABRA1 (0.33) | MEN1KMT2A | |
| SCHEMBL16889156 | 0.81 | EPHX1 (0.35) | CYP1A2KMT2A | |
| SCHEMBL17040334 | 0.79 | ATM (0.37) | CYP1A2CYP2C19TDP1TSHRALDH1A1 | |
| SCHEMBL2013971 | 0.78 | APLNR (0.38) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL20818779 | 0.77 | SLC1A2 (0.39) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL20818782 | 0.77 | SLC1A2 (0.39) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL20818852 | 0.77 | SLC1A2 (0.39) | APLNRCYP1A2SLC1A2SLC1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120785-B2 | Pyridyl aminopyridines as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-09-01 | — | — | US | disclosed |