Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691746 | 0.92 | APEX1 (0.49) | APEX1HTTAKR1B1THRBTDP1 | |
| SCHEMBL15691716 | 0.79 | MAPT (0.42) | APEX1HTTAKR1B1TDP1KMT2A | |
| SCHEMBL15691719 | 0.79 | APEX1 (0.67) | APEX1HTTTHRBTDP1TSHR | |
| SCHEMBL15691739 | 0.77 | APEX1 (0.39) | APEX1THRBTDP1CYP2D6KMT2A | |
| SCHEMBL17050306 | 0.76 | ALDH1A1 (0.37) | HTTTDP1TSHRKMT2AALDH1A1 | |
| SCHEMBL17050327 | 0.76 | APEX1 (0.58) | APEX1HTTTHRBTDP1TSHR | |
| SCHEMBL17050331 | 0.75 | MAPT (0.39) | APEX1HTTTDP1TSHRKMT2A | |
| SCHEMBL17050225 | 0.74 | APEX1 (0.39) | APEX1THRBTDP1KMT2A | |
| SCHEMBL17050168 | 0.74 | PGR (0.35) | APEX1CYP2D6KMT2APGR | |
| SCHEMBL29506890 | 0.73 | APEX1 (0.66) | APEX1AKR1B1THRBTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518150-B2 | Resin composition, stretched film, circularly polarizing plate, and image display device | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | RAD50, RAD54L, PUF60 | APEX1 3376/4885HTT 3447/4885AKR1B1 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.