SCHEMBL17050320

SCHEMBL17050320

CC(C1(C)c2ccccc2-c2ccccc21)C1(CC(=O)O)c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.42
THRB P10828 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 5/20 0.38
KIF11 P52732 4/20 0.38
MAPT P10636 1/20 0.35
ITGA4 P13612 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC25A5 P05141 1/20 0.34
AKR1B1 P15121 1/20 0.34
PDK2 Q15119 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15691731 0.90 APEX1 (0.47) APEX1THRBTDP1PKMKMT2A
SCHEMBL29197393 0.81 APEX1 (0.45) APEX1THRBTDP1PKMKMT2A
SCHEMBL7821184 0.76 APEX1 (0.46) APEX1THRBTDP1KIF11SLC25A5
SCHEMBL15691736 0.74 APEX1 (0.62) APEX1THRBTDP1KMT2AALDH1A1
SCHEMBL17051243 0.73 MAPT (0.48) APEX1THRBTDP1KMT2AALDH1A1
SCHEMBL15691714 0.73 ELANE (0.38) APEX1THRBTDP1KMT2AALDH1A1
SCHEMBL17051252 0.71 ALDH1A1 (0.42) KMT2AALDH1A1MAPTITGA4PDK2
SCHEMBL29506890 0.70 APEX1 (0.66) APEX1THRBTDP1PKMKMT2A
SCHEMBL15531786 0.70 APEX1 (0.66) APEX1THRBTDP1PKMKMT2A
SCHEMBL17050304 0.70 MAPT (0.45) TDP1KMT2AALDH1A1MAPTITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD50, RAD54L, PUF60 APEX1 3376/4885THRB 3988/4885TDP1 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.