Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506857 | 0.84 | APEX1 (0.47) | APEX1THRBTDP1CYP1A2TSHR | |
| SCHEMBL21219237 | 0.84 | APEX1 (0.47) | APEX1THRBTDP1CYP1A2TSHR | |
| SCHEMBL22870182 | 0.76 | ATM (0.37) | APEX1THRBTDP1TSHRATM | |
| SCHEMBL17050320 | 0.76 | APEX1 (0.42) | APEX1THRBTDP1CYP1A2KIF11 | |
| SCHEMBL15691731 | 0.74 | APEX1 (0.47) | APEX1THRBTDP1CYP1A2KIF11 | |
| SCHEMBL18906930 | 0.71 | PDK2 (0.40) | APEX1THRBTDP1ATMPDK2 | |
| SCHEMBL15691736 | 0.71 | APEX1 (0.62) | APEX1THRBTDP1CYP1A2TSHR | |
| SCHEMBL20143932 | 0.71 | PDK2 (0.39) | THRBTDP1ATMPDK2 | |
| SCHEMBL15691750 | 0.70 | THRB (0.44) | APEX1THRBTDP1CYP1A2TSHR | |
| SCHEMBL31272951 | 0.69 | APEX1 (0.46) | APEX1THRBTDP1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |