SCHEMBL17050342

SCHEMBL17050342

CCOC(=O)C1(CC2(CC3(CC)c4ccccc4-c4ccccc43)COC2)c2ccccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 4/20 0.35
GLA P06280 2/20 0.35
ALDH1A1 P00352 1/20 0.35
BLM P54132 2/20 0.35
KDM4E B2RXH2 2/20 0.35
TSHR P16473 2/20 0.35
GRM1 Q13255 1/20 0.35
PMP22 Q01453 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
APAF1 O14727 1/20 0.34
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
ABL1 P00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17050252 0.86 APEX1 (0.41) MEN1KMT2AMAPTGLAALDH1A1
SCHEMBL17050168 0.82 PGR (0.35) KMT2ACYP1A2CYP2C19APEX1
SCHEMBL15691711 0.80 ALDH1A1 (0.41) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL17051232 0.79 TSHR (0.43) MEN1KMT2AMAPTGLAALDH1A1
SCHEMBL17050331 0.79 MAPT (0.39) MEN1KMT2AMAPTALDH1A1TSHR
SCHEMBL15691738 0.79 APEX1 (0.43) MEN1KMT2AMAPTGLAALDH1A1
SCHEMBL17050250 0.77 APEX1 (0.43) MEN1KMT2AMAPTGLAALDH1A1
SCHEMBL17050327 0.77 APEX1 (0.58) MEN1KMT2ATSHRCYP2C19APEX1
SCHEMBL17050345 0.76 ALDH1A1 (0.37) MEN1KMT2AMAPTALDH1A1BLM
SCHEMBL15691721 0.75 POLB (0.41) MAPTALDH1A1KDM4ENSD2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD50, RAD54L, PUF60 MEN1 4576/4885KMT2A 3343/4885MAPT 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.