Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 3/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058018 | 0.88 | — | — | |
| SCHEMBL17058268 | 0.88 | — | — | |
| SCHEMBL11946291 | 0.86 | POLB (0.34) | UTRNFASNMGLLGPR119LMNA | |
| SCHEMBL17058559 | 0.83 | POLB (0.33) | — | |
| SCHEMBL17057972 | 0.82 | POLB (0.33) | — | |
| SCHEMBL11946289 | 0.82 | GPR119 (0.32) | FASNGPR119MAPT | |
| SCHEMBL17058475 | 0.81 | — | — | |
| SCHEMBL17058289 | 0.78 | NPBWR1 (0.34) | — | |
| SCHEMBL17058032 | 0.78 | — | — | |
| SCHEMBL17058558 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |