Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058460 | 0.85 | FFAR4 (0.32) | FFAR4ALDH1A1 | |
| SCHEMBL17058048 | 0.82 | PDE4A (0.35) | FFAR4GRM7ALDH1A1 | |
| SCHEMBL17058188 | 0.81 | NPC1 (0.39) | FFAR4ALDH1A1 | |
| SCHEMBL17058429 | 0.81 | SLC2A1 (0.31) | GRM7 | |
| SCHEMBL17058314 | 0.80 | SLC2A1 (0.30) | — | |
| SCHEMBL11945606 | 0.79 | POLB (0.37) | FFAR4ALDH1A1 | |
| SCHEMBL17058122 | 0.79 | NPC1 (0.35) | GRM7ALDH1A1 | |
| SCHEMBL17058316 | 0.77 | SLC2A1 (0.35) | FFAR4ALDH1A1 | |
| SCHEMBL17058167 | 0.77 | NPBWR1 (0.37) | ALDH1A1 | |
| SCHEMBL17058072 | 0.76 | MCHR1 (0.36) | FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |