Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058052 | 0.94 | NPSR1 (0.34) | SLC2A1SLC2A3MCHR1DCTPP1 | |
| SCHEMBL11944291 | 0.85 | MAPT (0.38) | SLC2A1SLC2A3GRM5DCTPP1 | |
| SCHEMBL17058048 | 0.80 | PDE4A (0.35) | SLC2A1SLC2A3MCHR1 | |
| SCHEMBL17058398 | 0.80 | SLC2A1 (0.33) | SLC2A1SLC2A3MCHR1DCTPP1 | |
| SCHEMBL17057784 | 0.80 | ALDH1A1 (0.35) | SLC2A1SLC2A3GRM5DCTPP1 | |
| SCHEMBL17058397 | 0.80 | ALDH1A1 (0.35) | SLC2A1SLC2A3GRM5DCTPP1 | |
| SCHEMBL17058243 | 0.80 | ALDH1A1 (0.36) | SLC2A1SLC2A3MCHR1DCTPP1 | |
| SCHEMBL11944190 | 0.78 | NPSR1 (0.40) | SLC2A1SLC2A3DCTPP1 | |
| SCHEMBL11944315 | 0.78 | MAPT (0.44) | DCTPP1 | |
| SCHEMBL17057800 | 0.78 | SLC2A1 (0.31) | SLC2A1SLC2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |