Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058017 | 0.86 | SLC2A1 (0.35) | SLC2A1SLC2A3NPBWR1MCHR1 | |
| SCHEMBL11945757 | 0.85 | MAPT (0.34) | SLC2A1SLC2A3NPBWR1MCHR1 | |
| SCHEMBL17058195 | 0.85 | SLC2A1 (0.34) | SLC2A1SLC2A3NPBWR1MCHR1 | |
| SCHEMBL17057833 | 0.82 | NPBWR1 (0.32) | SLC2A1SLC2A3NPBWR1MCHR1 | |
| SCHEMBL17058559 | 0.81 | POLB (0.33) | SLC2A1SLC2A3NPBWR1 | |
| SCHEMBL17058442 | 0.79 | DCTPP1 (0.39) | SLC2A1SLC2A3NPBWR1 | |
| SCHEMBL17058089 | 0.79 | SLC2A1 (0.32) | SLC2A1SLC2A3NPBWR1MCHR1 | |
| SCHEMBL17057972 | 0.77 | POLB (0.33) | SLC2A1SLC2A3 | |
| SCHEMBL11945751 | 0.76 | MAPT (0.36) | SLC2A1SLC2A3 | |
| SCHEMBL17058201 | 0.75 | POLB (0.34) | SLC2A1SLC2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137179-B1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-09-02 | — | — | EP | disclosed |