SCHEMBL17059012

SCHEMBL17059012

CCc1ccc(C(=O)OC2CCC(C)CC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.49
SCN1A P35498 2/20 0.48
SCN2A Q99250 2/20 0.48
SCN3A Q9NY46 2/20 0.48
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.45
SERPINE1 P05121 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
STS P08842 3/20 0.42
PLK1 P53350 1/20 0.42
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13025082 0.95 CYP19A1 (0.46) CYP19A1SCN1ASCN2ASCN3AALDH1A1
SCHEMBL27711586 0.93 SCN1A (0.53) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL4544917 0.93 SCN1A (0.53) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL9002108 0.90 SCN1A (0.56) CYP19A1SCN1ASCN2ASCN3AMEN1
SCHEMBL11128686 0.89 SCN1A (0.49) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL14511301 0.88 CYP19A1 (0.47) CYP19A1SCN1ASCN2ASCN3AALDH1A1
SCHEMBL20393532 0.87 ALDH1A1 (0.57) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL28596916 0.87 HTT (0.53) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL14510074 0.86 SCN1A (0.47) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL18313821 0.85 HTT (0.59) SCN1ASCN2ASCN3AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9500790-B2 Optical film, circularly polarizing plate, and image display device Konica Minolta, Inc. (JP) 2016-11-22 US disclosed
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247963-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE SUN2, HTR3D, CRY1 CYP19A1 351/4885SCN1A 3337/4885SCN2A 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.