SCHEMBL17059121

SCHEMBL17059121

C=CCN1COOCN(CC=C)C1=O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15827363 0.86 CYP3A4 (0.41) CYP3A4HDAC3HDAC4HDAC1HDAC7
SCHEMBL462082 0.78 CYP3A4 (0.46) CYP3A4HDAC3HDAC4HDAC1HDAC7
SCHEMBL20599288 0.74 CYP3A4 (0.42) CYP3A4HDAC3HDAC4HDAC1HDAC7
SCHEMBL31469053 0.73 CYP3A4 (0.41) CYP3A4HDAC3HDAC4HDAC1HDAC7
SCHEMBL17059114 0.72 FAAH (0.32)
SCHEMBL8773347 0.71 CYP3A4 (0.39) CYP3A4LMNAGAACA9
SCHEMBL9676287 0.71 CYP3A4 (0.39) CYP3A4HDAC3HDAC4HDAC1HDAC7
SCHEMBL11087524 0.70 GBA1 (0.36) GAA
SCHEMBL5139880 0.70
SCHEMBL31374506 0.70 CYP3A4 (0.38) CYP3A4HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2913331-A1 METHOD FOR PRODUCING EPOXY COMPOUND Nissan Chemical Industries, Ltd. (JP) 2015-09-02 EP disclosed