Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607808 | 0.82 | CSNK1A1 (0.42) | ALDH1A1L3MBTL1HSD11B1HSD11B2MEN1 | |
| SCHEMBL9607809 | 0.80 | CSNK1A1 (0.43) | ALDH1A1L3MBTL1HSD11B1HSD11B2MEN1 | |
| SCHEMBL9607818 | 0.75 | CSNK1A1 (0.44) | HSD11B1HSD11B2MEN1KMT2A | |
| SCHEMBL17059172 | 0.73 | OPRM1 (0.38) | HSD11B1MEN1KMT2A | |
| SCHEMBL24157288 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30877914 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30877902 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28378542 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30078304 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL54982 | 0.68 | ESR1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451807-B1 | CYCLIC TRIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2015-09-02 | — | — | EP | disclosed |