Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607818 | 0.83 | CSNK1A1 (0.44) | OPRM1ADORA2ADRD4PIK3CDPIK3R1 | |
| SCHEMBL9607809 | 0.79 | CSNK1A1 (0.43) | OPRM1ADORA2ADRD4CLK4MEN1 | |
| SCHEMBL9607808 | 0.77 | CSNK1A1 (0.42) | ADORA2ACLK4MEN1KMT2AHSD11B1 | |
| SCHEMBL17059348 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2AHSD11B1 | |
| SCHEMBL9607812 | 0.70 | HSD11B1 (0.41) | BACE1MEN1KMT2AHSD11B1 | |
| SCHEMBL9607820 | 0.69 | ALDH1A1 (0.43) | BACE1MEN1KMT2AHSD11B1 | |
| SCHEMBL976986 | 0.68 | BACE1 (0.46) | ADORA2AGSK3BPIK3CGBACE1HSD11B1 | |
| SCHEMBL2256573 | 0.65 | OPRM1 (0.67) | OPRM1DRD4GRIN2DGRIN3BCHRM2 | |
| SCHEMBL2256575 | 0.65 | OPRM1 (0.67) | OPRM1DRD4GRIN2DGRIN3BCHRM2 | |
| SCHEMBL2658676 | 0.65 | CLK4 (0.66) | OPRM1ADORA2ACYP2D6CHEK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451807-B1 | CYCLIC TRIAZO SODIUM CHANNEL BLOCKERS | UNIV GREENWICH (GB) | 2015-09-02 | — | — | EP | disclosed |