Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16288862 | 0.84 | KDM4E (0.31) | KDM4EMAPK1NPSR1 | |
| SCHEMBL16288863 | 0.79 | SMN1; SMN2 (0.46) | KDM4EMAPK1NPSR1 | |
| SCHEMBL4009656 | 0.78 | DYRK1B (0.39) | KDM4EMAPK1 | |
| SCHEMBL17059460 | 0.72 | RIPK2 (0.48) | KDM4EMAPK1NPSR1 | |
| SCHEMBL17059455 | 0.71 | PARP1 (0.46) | KDM4EMAPK1NPSR1 | |
| SCHEMBL1147789 | 0.71 | KDM4E (0.64) | KDM4EMAPK1NPSR1 | |
| SCHEMBL17033101 | 0.69 | CCR1 (0.42) | KDM4EMAPK1NPSR1 | |
| SCHEMBL17059467 | 0.69 | RIPK2 (0.36) | KDM4EMAPK1NPSR1 | |
| SCHEMBL17059457 | 0.69 | RIPK1 (0.49) | KDM4EMAPK1NPSR1 | |
| SCHEMBL17059454 | 0.69 | RIPK2 (0.54) | KDM4EMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | disclosed |