Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | LGMN | Q99538 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906256 | 0.86 | LGMN (0.40) | DPP4LGMNEGFRGAARAD52 | |
| SCHEMBL29661369 | 0.85 | SUV39H2 (0.45) | DPP4EGFRALDH1A1CYP3A4TSHR | |
| SCHEMBL310055 | 0.85 | SUV39H2 (0.45) | DPP4EGFRALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL29367159 | 0.84 | SUV39H2 (0.44) | DPP4EGFRALDH1A1CYP3A4TSHR | |
| SCHEMBL26484586 | 0.82 | EGFR (0.40) | DPP4EGFRALDH1A1CCR1DRD2 | |
| SCHEMBL17265199 | 0.82 | ALDH1A1 (0.46) | DPP4LGMNGAAALDH1A1CYP3A4 | |
| SCHEMBL10206172 | 0.81 | ACVR1 (0.43) | DPP4LGMNALDH1A1CYP3A4TSHR | |
| SCHEMBL29989539 | 0.80 | MEN1 (0.45) | DPP4LGMNGAAALDH1A1CYP3A4 | |
| SCHEMBL517608 | 0.80 | GAK (0.49) | DPP4LGMNGAAALDH1A1CYP3A4 | |
| SCHEMBL520153 | 0.80 | CCR4 (0.46) | DPP4LGMNALDH1A1CCR1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015127873-A1 | ARYLAMINO PYRAMIDINE COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS PREPARED THEREFROM | 上海海雁医药科技有限公司 | 2015-09-03 | — | — | WO | disclosed |