Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170605 | 0.71 | TP53 (0.46) | MAPTKDM4ELMNAHTTHPGD | |
| SCHEMBL6444260 | 0.70 | MAPT (0.77) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL170978 | 0.70 | KMT2A (0.51) | MAPTKDM4EMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9339159 | 0.67 | MAPT (0.77) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL2446110 | 0.67 | MAPT (0.66) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL30023422 | 0.67 | MAPT (0.66) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL9343741 | 0.66 | CA12 (0.63) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL28401771 | 0.66 | MAPT (0.64) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL28002548 | 0.65 | TSHR (0.51) | MAPTKDM4EHSD17B10ALOX15MAPK1 | |
| SCHEMBL29260274 | 0.65 | MAPT (0.67) | MAPTKDM4EHSD17B10ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |