Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170603 | 0.74 | ALDH1A1 (0.51) | HTTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL9537285 | 0.74 | MAPK8 (0.56) | ALDH1A1POLBKMT2ALMNAKDM4E | |
| SCHEMBL170978 | 0.74 | KMT2A (0.51) | HTTALDH1A1POLBKMT2ALMNA | |
| SCHEMBL11421766 | 0.74 | KMT2A (0.54) | HTTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL10412007 | 0.73 | PPARG (0.55) | MTNR1AMTNR1BLMNAKDM4EPPARG | |
| Hydrochloric Acid SCHEMBL10462662 | 0.72 | PPARG (0.54) | MTNR1AMTNR1BLMNAKDM4EPPARG | |
| SCHEMBL3762150 | 0.72 | RAB9A (0.55) | TP53HTTALDH1A1POLBKMT2A | |
| SCHEMBL170604 | 0.71 | MAPT (0.46) | TP53HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL11038273 | 0.71 | EDNRA (0.57) | HTTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL29986971 | 0.71 | MAPT (0.57) | TP53HTTALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |