Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 3/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | FAP | Q12884 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601776 | 1.00 | TPH1 (0.61) | TPH1DPP4SLC7A5PTGS1ALPI | |
| SCHEMBL838534 | 0.95 | SLC7A5 (0.62) | TPH1DPP4SLC7A5PTGS1ALPI | |
| SCHEMBL43594 | 0.95 | SLC7A5 (0.62) | TPH1DPP4SLC7A5PTGS1ALPI | |
| SCHEMBL43593 | 0.95 | SLC7A5 (0.62) | TPH1DPP4SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL10420165 | 0.93 | SLC7A5 (0.61) | TPH1DPP4SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL1183792 | 0.93 | SLC7A5 (0.61) | TPH1DPP4SLC7A5PTGS1ALPI | |
| Hydrochloric Acid SCHEMBL9710930 | 0.93 | SLC7A5 (0.61) | TPH1DPP4SLC7A5PTGS1ALPI | |
| SCHEMBL23077761 | 0.88 | SLC7A5 (0.54) | TPH1DPP4SLC7A5PTGS1ALPI | |
| SCHEMBL289815 | 0.87 | DPP4 (0.57) | TPH1DPP4MMP12MMP13FAP | |
| SCHEMBL289816 | 0.87 | DPP4 (0.57) | TPH1DPP4MMP12MMP13FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413693-B1 | SUBSTITUTED AZOANTHRACENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | VTV THERAPEUTICS LLC (US) | 2015-09-09 | — | — | EP | disclosed |