⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367379 | 0.69 | CYP2A6 (0.38) | — | |
| SCHEMBL222947 | 0.68 | — | — | |
| SCHEMBL4843148 | 0.65 | — | — | |
| SCHEMBL5746748 | 0.65 | — | — | |
| SCHEMBL891261 | 0.65 | KDM4E (0.39) | — | |
| SCHEMBL4670402 | 0.65 | — | — | |
| SCHEMBL2182857 | 0.65 | KDM4E (0.48) | — | |
| SCHEMBL3999585 | 0.63 | — | — | |
| SCHEMBL2171077 | 0.61 | — | — | |
| SCHEMBL7931429 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774795-B1 | 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS | UNIV MASARYKOVA (CZ) | 2022-03-16 | — | — | EP | claimed |
| CN-102666531-A | Heterocyclic-substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER SCHERING PHARMA AG | 2012-09-12 | — | — | CN | claimed |
| CN-102639494-A | Sulphone compounds and methods of making and using same | ZAFGEN CORP | 2012-08-15 | — | — | CN | claimed |
| CN-102596961-A | Imidazo[1,2-b]pyridazine derivatives and their use as pde10 inhibitors | JANSSEN PHARMACEUTICA NV | 2012-07-18 | — | — | CN | claimed |
| WO-2012074980-A2 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES | DARA BIOSCIENCES, INC. (US) | 2012-06-07 | — | — | WO | claimed |
| CN-101663301-B | Substituted imidazopyridine derivatives as melanocortin-4 receptor antagonists | SANTHERA PHARMACEUTICALS CH | 2012-06-06 | — | — | CN | claimed |
| CN-102105449-A | Arylsulfonamide compounds, compositions and methods of use | GENENTECH INC | 2011-06-22 | — | — | CN | claimed |
| CN-102099339-A | Benzazepine derivatives and their use as hstamine h3 antagonists | 武田药品工业株式会社 | 2011-06-15 | — | — | CN | claimed |
| CN-102015726-A | Heterocyclic derivatives | C & C RES LAB | 2011-04-13 | — | — | CN | claimed |
| CN-101998963-A | Insecticidal composition | DOW AGROSCIENCES LLC (US) | 2011-03-30 | — | — | CN | claimed |
| CN-1261276-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2000-07-26 | — | — | CN | claimed |
| CN-1046725-C | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-11-24 | — | — | CN | claimed |
| CN-1216043-A | Substd. benzenesulfonamide derivs as prodrugs of COX-2 inhibitors | SEARLE & CO (US) | 1999-05-05 | — | — | CN | claimed |
| CN-1192697-A | Epoxy-steroidal aldosterone antagonist and angiotensin II antagonist combination therapy for the treatment of congestive heart failure | SEARLE & CO (US) | 1998-09-09 | — | — | CN | claimed |
| CN-1192696-A | Spironolactone and angiotensin 2 antagonist combination therapy for treatment of congestive heart failure | SEARLE & CO (US) | 1998-09-09 | — | — | CN | claimed |
| CN-1151161-A | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | CN | claimed |
| CN-1117731-A | Heteroaromatic compounds with antipsychotic activity | WELLCOME FOUND (GB) | 1996-02-28 | — | — | CN | claimed |
| EP-0383281-B1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO LTD (JP) | 1994-08-17 | — | — | EP | claimed |
| CN-1079966-A | Heterogeneous ring compound, its preparation and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | CN | claimed |
| CN-1067890-A | Heterogeneous ring compound, its preparation and application | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-01-13 | — | — | CN | claimed |