SCHEMBL17061024

SCHEMBL17061024

[Cr].c1ccc(-c2ccc3c([nH]c4ccccc43)c2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.50
ESR2 Q92731 3/20 0.50
HTR2B P41595 1/20 0.49
HTR5A P47898 1/20 0.49
TDO2 P48775 1/20 0.49
KIF11 P52732 5/20 0.49
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193017 0.98 ESR1 (0.52) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL30022621 0.98 ESR1 (0.52) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL30302859 0.97 ESR1 (0.50) ESR1ESR2HTR2BHTR5ATDO2
Ammonia Solution, Strong SCHEMBL14343305 0.97 ESR1 (0.50) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL3275555 0.90 HPGD (0.47) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL29986522 0.90 GABRP (0.49) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL15771767 0.89 ESR1 (0.44) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL29088058 0.89 ESR1 (0.59) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL30022347 0.89 ESR1 (0.46) ESR1ESR2HTR2BHTR5ATDO2
SCHEMBL3270151 0.88 MAOA (0.48) ESR1ESR2HTR2BHTR5ATDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150253296-A1 METHOD FOR DETECTING ANALYTES METROHM AG (CH) 2015-09-10 US disclosed
CN-104903723-A Method for detecting analytes METROHM AG 2015-09-09 CN disclosed