Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LATS1 | O95835 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005773 | 0.88 | CYP3A4 (0.52) | CYP3A4CDC7CDK9KDM4EALDH1A1 | |
| SCHEMBL4309528 | 0.86 | CDC7 (0.62) | CDC7CDK9KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3554851 | 0.82 | CDC7 (0.48) | CYP3A4CDC7CDK9KDM4ESIRT3 | |
| SCHEMBL29534523 | 0.81 | KIF18A (0.47) | CYP3A4CDC7CDK9SIRT3TDP1 | |
| SCHEMBL29403120 | 0.81 | KIF18A (0.47) | CYP3A4CDC7CDK9SIRT3TDP1 | |
| SCHEMBL3081421 | 0.78 | NPC1 (0.70) | KDM4EALDH1A1HSD17B10NPC1POLB | |
| SCHEMBL28711057 | 0.77 | SIRT3 (0.49) | CYP3A4KDM4EALDH1A1HSD17B10SIRT3 | |
| SCHEMBL18228362 | 0.77 | CYP3A4 (0.54) | CYP3A4LATS1BCL2A1POLBKMT2A | |
| SCHEMBL28030748 | 0.76 | KDM4E (0.46) | CYP3A4KDM4EALDH1A1HSD17B10CHEK1 | |
| SCHEMBL28030745 | 0.76 | CYP3A4 (0.42) | CYP3A4CDC7CDK9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250794-A1 | MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | TAIVEX THERAPEUTICS CORP (TW) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250794-A1 | MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR | WEE1, WEE2, NEK11 | CYP3A4 3983/4885CDC7 28/4885CDK9 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.