SCHEMBL1706267

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1703264	1.00	MAPT (0.49)	MAPTCYP1A2CYP24A1NPC1RAB9A
	SCHEMBL15426321	0.85	CYP1A2 (0.55)	MAPTCYP1A2NPC1RAB9ATRPA1
	SCHEMBL66965	0.85	CYP1A2 (0.55)	MAPTCYP1A2NPC1RAB9ATRPA1
	SCHEMBL1704939	0.84	ESR1 (0.46)	MAPTSLC7A5BLM
	SCHEMBL20363221	0.83	ALPI (0.50)	CYP1A2NPC1RAB9ATRPA1ALPI
	SCHEMBL12650596	0.83	ALPI (0.50)	CYP1A2NPC1RAB9ATRPA1ALPI
	SCHEMBL1705697	0.82	TSHR (0.50)	CYP1A2CYP24A1NPC1RAB9APOLB
	SCHEMBL1703204	0.82	TSHR (0.50)	CYP1A2CYP24A1NPC1RAB9APOLB
	SCHEMBL9692685	0.81	CYP1A2 (0.47)	MAPTCYP1A2NPC1RAB9ATRPA1
	SCHEMBL15426320	0.81	EPHX1 (0.53)	CYP1A2NPC1RAB9ATRPA1ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.