SCHEMBL1706310

SCHEMBL1706310

CCCCC1CCCCNC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 12/20 0.48
CCR1 P32246 1/20 0.44
CCR5 P51681 1/20 0.44
CXCR4 P61073 1/20 0.44
HTT P42858 1/20 0.42
CYP19A1 P11511 1/20 0.40
CYP1A2 P05177 1/20 0.39
PSEN1 P49768 1/20 0.39
PSEN2 P49810 1/20 0.39
APH1B Q8WW43 1/20 0.39
NCSTN Q92542 1/20 0.39
APH1A Q96BI3 1/20 0.39
PSENEN Q9NZ42 1/20 0.39
MMP1 P03956 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
NOD1 Q9Y239 1/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27607336 0.98 CCR2 (0.47) CCR2CCR1CCR5CXCR4HTT
SCHEMBL181231 0.95 CCR2 (0.51) CCR2CCR1CCR5CXCR4HTT
SCHEMBL5754395 0.95 CCR2 (0.42) CCR2CCR1CCR5CXCR4HTT
SCHEMBL874895 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL28510248 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL229898 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL9003899 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL15253305 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL5871975 0.93 CCR2 (0.52) CCR2CCR1CCR5CXCR4HTT
SCHEMBL1401505 0.89 CCR2 (0.46) CCR2CCR1CCR5CXCR4CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3775138-A1 COMPOSITIONS AND METHODS FOR CLEANING AND STRIPPING AdvanSix Resins & Chemicals LLC (US) 2021-02-17 EP claimed
WO-2019191245-A1 COMPOSITIONS AND METHODS FOR CLEANING AND STRIPPING ADVANSIX RESINS & CHEMICALS LLC (US) 2019-10-03 WO claimed
CN-1329430-C Polyamides BASF AG (DE) 2007-08-01 CN claimed
US-12024584-B2 Methods and compositions for polyurethane dispersions using caprolactam-derived solvents ADVANSIX RESINS & CHEMICALS LLC (US) 2024-07-02 US disclosed
US-20230093825-A1 METHODS AND COMPOSITIONS FOR POLYURETHANE DISPERSIONS USING CAPROLACTAM-DERIVED SOLVENTS ADVANSIX RESINS & CHEMICALS LLC (US) 2023-03-30 US disclosed
EP-4134385-A1 METHODS AND COMPOSITIONS FOR POLYURETHANE DISPERSIONS USING CAPROLACTAM-DERIVED SOLVENTS AdvanSix Resins & Chemicals LLC (US) 2023-02-15 EP disclosed
US-11542360-B2 Methods and compositions for polyurethane dispersions using caprolactam-derived solvents ADVANSIX RESINS & CHEMICALS LLC (US) 2023-01-03 US disclosed
EP-3510070-B1 METHODS AND COMPOSITIONS FOR POLYURETHANE DISPERSIONS USING CAPROLACTAM-DERIVED SOLVENTS ADVANSIX RESINS & CHEMICALS LLC (US) 2022-08-24 EP disclosed
EP-3894506-A1 COMPOSITIONS INCLUDING PVC OR CPVC AdvanSix Resins & Chemicals LLC (US) 2021-10-20 EP disclosed
EP-3774982-A1 THIXOTROPIC RHEOLOGY MODIFYING AGENT COMPOSITIONS AdvanSix Resins & Chemicals LLC (US) 2021-02-17 EP disclosed
EP-3775138-A1 COMPOSITIONS AND METHODS FOR CLEANING AND STRIPPING AdvanSix Resins & Chemicals LLC (US) 2021-02-17 EP disclosed
CN-1137268-A Amidino derivatives useful as nitric oxide synthase inhibitors SEARLE & CO (US) 1996-12-04 CN disclosed
EP-0724570-A1 AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE & CO. (US) 1996-08-07 EP disclosed
WO-1995011231-A1 AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G. D. SEARLE & CO. (US) 1995-04-27 WO disclosed
EP-0409105-A2 Process for preparing polyarylene sulfides IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-01-23 EP disclosed
EP-0405609-A2 Process for preparing polyarylene sulfides IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-01-02 EP disclosed
EP-0279217-A1 Process for the preparation of poly(arylensulfides) with adjustable melt viscosity BAYER AG (DE) 1988-08-24 EP disclosed
EP-0050810-B1 COPOLYMERISATES FROM ALIPHATIC POLYCARBONATES AND LACTAMS BAYER AG (DE) 1985-01-30 EP disclosed
EP-0050810-A1 Copolymerisates from aliphatic polycarbonates and lactams BAYER AG (DE) 1982-05-05 EP disclosed
US-3960890-A CONTROL OF ECTOPARASITES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed