Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 10/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28510248 | 1.00 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL5871975 | 1.00 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL229898 | 1.00 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL15253305 | 1.00 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL874895 | 1.00 | CCR2 (0.52) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL181231 | 0.98 | CCR2 (0.51) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL9978692 | 0.95 | CCR2 (0.47) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL7622441 | 0.95 | CCR2 (0.47) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL1401505 | 0.93 | CCR2 (0.46) | CCR2CCR1CCR5CXCR4PSEN1 | |
| SCHEMBL1706310 | 0.93 | CCR2 (0.48) | CCR2CCR1CCR5CXCR4PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527797-A | IONTOPHORESIS | MACROCHEM CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0552879-A1 | Improved iontophoretic administration of drugs | MACROCHEM CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |