Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.80 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.80 |
| ▸ | RELA | Q04206 | 3/20 | 0.80 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.80 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.80 |
| ▸ | EGFR | P00533 | 1/20 | 0.80 |
| ▸ | SRC | P12931 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 1/20 | 0.80 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.80 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butein SCHEMBL25209583 | 1.00 | KMT2A (0.80) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL30383523 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL505501 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL243647 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL25202104 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL243646 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL139243 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL29724857 | 0.89 | KMT2A (1.00) | KMT2AMEN1NFKB1NFKB2RELA | |
| Butein SCHEMBL25200377 | 0.88 | KMT2A (0.97) | KMT2AMEN1NFKB1NFKB2RELA | |
| SCHEMBL19645123 | 0.83 | MEN1 (0.72) | KMT2AMEN1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | claimed |
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | disclosed |