Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436874 | 0.81 | OPRM1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL781667 | 0.79 | OPRM1 (0.55) | OPRM1SLC22A1ABCB1OPRD1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11563478 | 0.78 | OPRM1 (0.54) | OPRM1SLC22A1ABCB1OPRD1SMN1; SMN2 | |
| Citric Acid SCHEMBL5617042 | 0.76 | OPRM1 (0.50) | OPRM1SLC22A1ABCB1OPRD1 | |
| Sufentanil SCHEMBL27722103 | 0.75 | OPRM1 (1.00) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL26728 | 0.75 | OPRM1 (1.00) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28438312 | 0.74 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| SCHEMBL29689972 | 0.74 | OPRM1 (0.54) | OPRM1SLC22A1ABCB1OPRD1 | |
| Sufentanil SCHEMBL780198 | 0.74 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28432948 | 0.74 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250733-A1 | ORAL DRUG DELIVERY FORMULATIONS | ODIDI ISA (CA) | 2015-09-10 | — | — | US | disclosed |