Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5270544 | 1.00 | LMNA (0.47) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL258132 | 1.00 | LMNA (0.47) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL987788 | 0.95 | LMNA (0.44) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL7783115 | 0.95 | LMNA (0.44) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL3430407 | 0.95 | LMNA (0.44) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL1628229 | 0.95 | LMNA (0.54) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL4407755 | 0.94 | LMNA (0.43) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL14563189 | 0.94 | LMNA (0.43) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL8350505 | 0.94 | TDP1 (0.55) | LMNAALDH1A1TSHRTDP1CES2 | |
| Styrene SCHEMBL905411 | 0.94 | TDP1 (0.55) | LMNAALDH1A1TSHRTDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| EP-3114150-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134591-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2015-09-11 | — | — | WO | disclosed |
| US-8980824-B2 | Tubulysin compounds, methods of making and use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | GLO1, TET1, RIOX2 | LMNA 3944/4885ALDH1A1 235/4885TSHR 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.