SCHEMBL17065846

SCHEMBL17065846

Cc1ccc(CC[Si]2(C)CCCCO2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
HRH1 P35367 1/20 0.35
KCNH2 Q12809 1/20 0.32
IDO1 P14902 1/20 0.31
IGF1R P08069 1/20 0.31
ALOX15 P16050 1/20 0.31
NAAA Q02083 1/20 0.31
ALDH1A1 P00352 2/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853648 0.70
SCHEMBL9802444 0.70 ESR1 (0.36) TAAR1ALOX15ALDH1A1
SCHEMBL9308520 0.69 TP53 (0.31)
SCHEMBL6842421 0.69
Ammonia Solution, Strong SCHEMBL28966876 0.69
SCHEMBL6061574 0.68
SCHEMBL10691703 0.68 SMN1; SMN2 (0.40) HRH3CYP1A2TAAR1IDO1ALDH1A1
Methyl Alcohol SCHEMBL28320506 0.67
SCHEMBL7058250 0.67
SCHEMBL7602540 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110519-A2 ANTI-FOAM COMPOSITIONS Shin-Etsu Chemical Co., Ltd. (JP) 2017-01-04 EP disclosed
WO-2015132669-A2 ANTI-FOAM COMPOSITIONS SHIIN-ETSU CHEMICAL CO., LTD (JP) 2015-09-11 WO disclosed