SCHEMBL9802444

SCHEMBL9802444

C[Si]1(Cc2ccc(O)cc2)CCCCO1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.36
ESR2 Q92731 5/20 0.33
CA2 P00918 2/20 0.32
ABAT P80404 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
PLEC Q15149 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308520 0.83 TP53 (0.31) POLB
SCHEMBL10691703 0.81 SMN1; SMN2 (0.40) ALDH1A1TAAR1SIGMAR1SLC6A2
SCHEMBL17065846 0.70 HRH3 (0.39) ALDH1A1ALOX15TAAR1
Bisphenol A SCHEMBL11332886 0.68 ESR1 (0.39) ESR1ESR2KDM4EALDH1A1HPGD
Phenol SCHEMBL1440050 0.68 CA12 (0.42) ESR1ESR2CA2ALDH1A1ACHE
SCHEMBL9351404 0.66 KDM4E (0.32) CA2KDM4EMEN1ALDH1A1MAPT
SCHEMBL359200 0.65
SCHEMBL2404033 0.65 TAAR1 (0.39) KDM4EALDH1A1HPGDL3MBTL1TAAR1
SCHEMBL9576219 0.64
SCHEMBL9064718 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0229629-B1 PHOTOSENSITIVE RESIN COMPOSITION HITACHI, LTD. (JP) 1991-03-20 EP disclosed