Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308520 | 0.80 | TP53 (0.31) | — | |
| 1,4-Dimethoxybenzene SCHEMBL29157786 | 0.65 | CA1 (0.58) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL338865 | 0.65 | SLC6A3 (0.33) | SMN1; SMN2SLC6A3TAAR1SIGMAR1ALDH1A1 | |
| SCHEMBL12377371 | 0.64 | — | — | |
| SCHEMBL972798 | 0.62 | — | — | |
| SCHEMBL6301896 | 0.61 | HPGD (0.55) | SMN1; SMN2ALDH1A1 | |
| 1,4-Dimethoxybenzene SCHEMBL28282673 | 0.61 | CA1 (0.92) | IDO1LTA4HALDH1A1PKM | |
| SCHEMBL982940 | 0.61 | IDO1 (0.58) | SMN1; SMN2IDO1SLC6A4AGXTLTA4H | |
| SCHEMBL21825719 | 0.61 | IDO1 (0.58) | SMN1; SMN2IDO1SLC6A4AGXTLTA4H | |
| SCHEMBL979649 | 0.61 | IDO1 (0.58) | SMN1; SMN2IDO1SLC6A4AGXTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745169-A | Alkali-soluble siloxane polymer, silmethylene polymer, and polyorganosilsesquioxane polymer | HITACHI, LTD. (JP) | 1988-05-17 | — | — | US | disclosed |
| EP-0204963-A2 | Use of Alkali-Soluble Polyorganosilsesquioxane Polymers in a resist for preparing electronics parts. | HITACHI, LTD. (JP) | 1986-12-17 | — | — | EP | disclosed |